Research progress on the West Nile virus inhibitors
10.16438/j.0513-4870.2019-1017
- VernacularTitle:西尼罗病毒抑制剂研究进展
- Author:
Rui-peng LIANG
1
;
Tong ZHAO
1
;
Peng ZHAN
1
;
Xin-yong LIU
1
Author Information
1. Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China
- Publication Type:Research Article
- Keywords:
West Nile virus;
West Nile fever;
inhibitor;
rug target;
rug design
- From:
Acta Pharmaceutica Sinica
2020;55(4):763-772
- CountryChina
- Language:Chinese
-
Abstract:
West Nile virus is a flavivirus transmitted by culex mosquitoes. People are generally susceptible to it, West Nile virus infection can cause west Nile fever, which can develop West Nile viral encephalitis and even lead to death. There are currently no approved specific antiviral drugs against West Nile virus. Therefore, seeking effective West Nile virus inhibitors is a hot topic in current community of medicinal chemistry. In this article, based on the main targets of West Nile virus, we summarize the new progress research on West Nile virus inhibitors.
