Advances in Chikungunya virus inhibitors
10.16438/j.0513-4870.2019-1002
- VernacularTitle:基孔肯雅病毒抑制剂研究进展
- Author:
Xiang-yi JIANG
1
;
Jing LI
1
;
Xiao-ying WEI
1
;
Peng ZHAN
1
;
Xin-yong LIU
1
Author Information
1. Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China
- Publication Type:Research Article
- Keywords:
Chikungunya fever;
Chikungunya virus;
inhibitor;
antiviral drug;
medicinal chemistry strategy
- From:
Acta Pharmaceutica Sinica
2020;55(4):754-762
- CountryChina
- Language:Chinese
-
Abstract:
Chikungunya fever (CHIKF) is an arthropod-borne infection disease caused by Chikungunya virus (CHIKV), which represents a serious health problem worldwide. There is no antiviral drugs treatment for CHIKV infections, neither is there an effective vaccine for prevention of the disease. Herein, we reviewed the recent reported and classical inhibitors of CHIKV, and summarized the medicinal chemistry strategies for discovering CHIKV inhibitors.
