Strategies in the evaluation of coagulation status in patients with liver failure
10.3969/j.issn.1001-5256.2020.04.049
- VernacularTitle:肝衰竭患者的出凝血状态评估策略
- Author:
Binyue LYU
1
;
Qian LI
Author Information
1. ICU, Tianjin Second People’s Hospital, Tianjin Medical University, Tianjin 300192, China
- Publication Type:Research Article
- Keywords:
liver failure;
hemorrhage;
coagulation
- From:
Journal of Clinical Hepatology
2020;36(4):928-931
- CountryChina
- Language:Chinese
-
Abstract:
Complex coagulation disorders are observed in patients with liver failure, and currently there is no comprehensive evaluation system to assess the risk of bleeding and thrombosis in such patients. This article summarizes the application of routine coagulation test and the hot techniques for coagulation assessment such as viscoelasticity test and thrombin generation analysis in patients with liver failure. The analysis shows that a single method has poor accuracy in evaluating the risk of bleeding and thrombosis and further exploration of a more accurate and effective assessment method should comprehensively consider the factors such as coagulation and anticoagulation factors, fibrinolytic system, platelet function, and systemic status of patients with liver failure, with reference to emerging coagulation process measurement techniques.
