Influence of perivascular space enlargement on the prognosis of acute anterior circulation mild stroke
10.16571/j.cnki.1008-8199.2018.07.010
- VernacularTitle: 扩大血管周围间隙对急性前循环轻型卒中预后的影响
- Author:
Kun CHEN
1
;
Li-juan LIU
1
;
De-chang HAN
1
;
Hai-ping WANG
1
;
Hui LI
1
;
Bao-quan LU
1
Author Information
1. Department of Neurology,the Affiliated Tangshan Gongren Hospital of North China University of Science and Technology,Tangshan 063000,Hebei,China
- Publication Type:Journal Article
- Keywords:
enlarged perivascular space;
cerebral infarction;
hypertension;
leukoaraiosis
- From:
Journal of Medical Postgraduates
2018;31(7):719-721
- CountryChina
- Language:Chinese
-
Abstract:
Objective Few studies are reported on the influence of perivascular space enlargement (PVSE) on the prognosis of cerebral infarction. This study was to investigate the clinical correlation of EPVS in the basal ganglia and central semiovale with the prognosis of the first acute cerebral infarction (ACI) with anterior circulation mild small-artery occlusion (SAO).Methods We treated 137 cases of the first ACI with anterior circulation mild SAO in Tangshan Gongren Hospital from August 2015 to October 2016. According to the scores on PVSE in the basal ganglia and central semiovale, we divided the patients into a mild PVSE (score: 0-1) and a severe PVSE group (score: 2-4). Based on the National Institutes of Health Stroke Scale (NHISS) and the modified Rankin Scale (MRS) scores, we classified the outcome of neurological function recovery as good (MRS≥2) and poor (MRS<2) and analyzed the risk factors for the poor prognosis of ACI by logistic regression analysis.Results There were 60 cases of severe and 77 cases of mild PVSE in the in the basal ganglia as compared with 57 cases of severe and 80 cases of mild PVSE in the in the central semiovale. Good prognosis was achieved in 97 cases while poor prognosis observed in 40. Multivariate logistic regression analysis showed that the risk factors for the poor prognosis of ACI included NHISS at the onset (OR=5.393, 95% CI: 1.858-15.654), hypertension (OR=3.729, 95% CI: 1.310-10.610), and the severity of PVSE in the basal ganglia (OR=3.137, 95% CI: 1.343-7.325).Conclusion For the first acute cerebral infarction with anterior circulation mild small-artery occlusion, the severity of PVSE in the basal ganglia is an important factor affecting the recovery of neurological function.
