Comparative Study of Transrectal Real-time Tissue Elastography and Magnetic Resonance Diffusion-Weighted Imaging in the Diagnosis and Guided Biopsy of Prostate Cancer
- VernacularTitle:超声弹性成像与磁共振弥散成像引导穿刺活检前列腺癌诊断的对比研究
- Author:
Hong-xia LU
1
;
Jian-xun SONG
1
;
Ting-ting WU
2
;
Ming-hui TONG
2
;
Tao LIANG
1
Author Information
1. Department of Ultrasound，the Second Affiliated Hospital of Shenzhen University，Shenzhen 518100，China；
2. Department of Ultrasound，the Second Hospital of Lanzhou University，Lanzhou 730030，China
- Publication Type:Journal Article
- Keywords:
prostate cancer, elasticity imaging techniques, magnetic resonance imaging, diffusion-weighted imaging, Gleason score
- From:
Journal of Sun Yat-sen University(Medical Sciences)
2019;40(4):592-597
- CountryChina
- Language:Chinese
-
Abstract:
【Objectives】 To comparatively analyze the diagnostic performance of transrectal real- time elastography（TRTE）and magnetic resonance diffusion- weighted imaging （DWI）in differentiating benign from malignant prostatic lesions，to evaluate the value of the two methods in guided prostate biopsy，and to investigate the correlation between the two methods and Gleason scores. 【Methods】 A total of 126 patients with suspected prostate cancer underwent prostate biopsy. Preoperative tests of TRTE and DWI were performed in all of the included patients. Combined with pathological results，the diagnostic efficacy of TRTE and DWI for prostate cancer and the effects of prostate biopsy guided by the two methods were compared ，and the relationship between the elastography score and ADC value and Gleason scores were also evaluated.【Results】 The sensitivity，specificity，accuracy of diagnosing prostate cancer by TRTE were 78.8% ，78.3% ，78.6% ，the sensitivity，specificity，accuracy of diagnosing prostate cancer by DWI were 87.9% ，90% ，88.9% ， there was no significant difference of sensitivity and specificity between the two groups（P > 0.05），and the accuracy was statistically different（P < 0.05）. The AUC of elastography score and ADC value were 0.859 and 0.906，the accuracy of the diagnosis of benign and malignant prostate lesions by ADC value method was higher than elastography score ，but there was no statistically significant difference （P > 0.05）. A significant positive correlation was found between elastography score and Gleason scores，while a significant negative correlation was found between ADC value and Gleason scores.【Conclusions】TRTE and DWI is valuable in diagnosis of prostatic lesions. Biopsy guided by the two methods can improve the detection rate of prostate cancer and can provide indicative evidence for tumor differentiation analysis.
