Host Cell Responses to Dengue Virus
- VernacularTitle:宿主细胞抗登革病毒的应答
- Author:
Ping ZHANG
1
Author Information
1. Department of Immunology，Zhongshan School of Medicine Sun Yat-sen University，Guangzhou 510080，China
- Publication Type:Journal Article
- Keywords:
dengue virus, cell response, innate immunity, adaptive immune responses, cell death, unfolded protein response, autophagy, stress granule
- From:
Journal of Sun Yat-sen University(Medical Sciences)
2020;41(1):16-23
- CountryChina
- Language:Chinese
-
Abstract:
Recent outbreak of dengue virus （DENV） in subtropics and tropics and the increasing incidence of DENV infection have seriously threatened the public health. Upon virus infection，the host cells rapidly elicit various responses through activating different signaling pathways，to fight against the invasion of DENV. On the other hand，dengue virus has evolved many strategies of escaping，antagonizing or even utilizing these host responses. This review summarizes the progress of molecular biology of DENV and the cellular responses against DENV infection，including innate immune response，adaptive immune response，cell death，autophagy，unfolded protein response，and stress granule formation.
