Two new monoterpenoids of Zingiber officinale peel
10.16438/j.0513-4870.2019-0803
- VernacularTitle:姜皮中两个新的单萜类化合物
- Author:
Yan GUO
1
;
Yan-zhi WANG
2
;
Zhi-pin XU
1
;
Man-qian LI
1
;
Xiao-juan ZHANG
1
;
Yu-fei LIU
1
;
Xue-yu HU
1
;
Wei-sheng FENG
2
Author Information
1. School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China
2. School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China; Co-construction Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases by Henan & Education Ministry of P. R. China, Zhengzhou 450046, China
- Publication Type:Research Article
- Keywords:
Zingiberaceae;
italic>Zingiber officinale peel;
terpenoid;
structural identification
- From:
Acta Pharmaceutica Sinica
2020;55(3):484-488
- CountryChina
- Language:Chinese
-
Abstract:
The chemical constituents of Zingiber officinale peel were isolated and purified by various chromatographic separation techniques such as Diaion HP-20, MCI Gel CHP-20, Sephadex LH-20, ODS, silica gel and semi-preparative HPLC. Seven terpenoids were identified by physicochemical properties and spectral data: (4R,6S)-1-(hydroxymethyl)-5,5-dimethylbicyclo[3.1.1]hept-2-en-4-ol (1), 4-(hydroxymethyl)-1-isopropylcyclohex-2-ene-3,4-diol (2), 3,5,6-trihydroxy-7-megastigmen-9-one (3), 3-(3-hydroxybutyl)-2,4,4-trimethyl-2,5-cyclohexadien-1-one (4), angelicoidenol (5), grasshopper ketone (6), and dihydrophaseic acid (7), in which compounds 1, 2 are new compounds, named: (4R,6S)-1-(hydroxymethyl)-5,5-dimethylbicyclo[3.1.1]hept-2-en-4-ol and 4-(hydroxymethyl)-1-isopropylcyclohex-2-ene-3,4-diol, and compounds 3-7 were obtained from this plant for the first time.
