Research progress of scaffolds for promoting the vascularization of regenerated dental pulp
10.12016/j.issn.2096-1456.2020.03.012
- Author:
LIU Huimin
1
;
LI Xiangwei
1
Author Information
1. Department of Conservative Dentistry and Endodontics, School and Hospital of Stomatology, Jilin University
- Publication Type:Review
- Keywords:
dental pulp vascular;
dental pulp regeneration;
vascularization;
tissue engineering;
scaffold material;
Chitosan;
injectable hydrogels/microspheres;
biomimetic scaffolds
- From:
Journal of Prevention and Treatment for Stomatological Diseases
2020;28(3):200-204
- CountryChina
- Language:Chinese
-
Abstract:
Endothelial regeneration is a research hotspot in the field of dental pulp. The regeneration of endodontic blood flow is the bottleneck of dental pulp regeneration, and the applied scaffold material is the key to revascularization. Stent materials were reviewed. The literature review Results show that, depending on the source of the stent material used for endodontic revascularization, there are mainly natural, synthetic and composite materials. The natural scaffold materials used for vascular regeneration include chitosan, hyaluronic acid, bacterial cellulose, and proanthocyanidin; artificial scaffold materials include hydrogel, cryogel, and electrospinning. The bionic composite scaffold system with a double-layer tubular structure is low immunogenicity and good biocompatibility. Studies on the scaffold materials of bionic extracellular matrix, such as injectable hydrogels/microspheres, have promoted the development of dental pulp regeneration, that is, uniformly distributed scaffold materials in the root canal promote the generation of pulp-like tissue; Whether dental pulp tissue can establish effective blood circulation through the apical foramen remains a great challenge.
- Full text:促进再生牙髓血管化的支架研究进展.pdf
