Relationship between dietary vitamin C and Type 2 diabetes.
10.11817/j.issn.1672-7347.2015.10.009
- Author:
Xiaoxiao LI
1
;
Xinliang WANG
1
;
Jie WEI
1
;
Tubao YANG
1
Author Information
1. Department of Epidemiology and Health Statistics, School of Public Health, Central South University, Changsha 410078, China.
- Publication Type:Journal Article
- MeSH:
Ascorbic Acid;
administration & dosage;
Blood Glucose;
analysis;
Blood Pressure;
Body Height;
Body Mass Index;
Body Weight;
Case-Control Studies;
Diabetes Mellitus, Type 2;
epidemiology;
Diet;
Dietary Supplements;
Humans;
Logistic Models;
Nutritional Status;
Risk Factors;
Surveys and Questionnaires;
Vitamins;
administration & dosage
- From:
Journal of Central South University(Medical Sciences)
2015;40(10):1109-1114
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To examine the correlation between dietary vitamin C intake and Type 2 diabetes.
METHODS:A total of 5 168 participants from Xiangya Hospital, Central South University were randomly selected. According to the vitamin C intake, the participants were divided into 5 groups: a Q1 group (n=1 033), a Q2 group (n=1 034), a Q3 group (n=1 034), a Q4 group (n=1 034) and a Q5 group (n=1 033). They were also divided into a Type 2 diabetes group (n=502) and a non-diabetes group (n=4 666). The height, weight, and blood pressure were measured, and vitamin C intake and other dairy consumption were evaluated using a food frequency questionnaire and fasting plasma glucose (FPG). The analysis of variance (ANOVA), Chi-square test, Mann-Whitney U test and logistic regression model were used to analyze the relationship between dietary vitamin C and Type 2 diabetes.
RESULTS:The univariate analysis showed that there were significant differences in the vitamin C consumption in energy intake, activity level, dietary fiber intake, nutritional supplementation status, drinking or not drinking, education level among the different vitamin C intake groups (all P<0.05). There were also significant differences in age, sex, body mass index (BMI), smoking status and vitamin C intake between the Type 2 diabetes group and the non-diabetes group (all P<0.05). After the adjustment for age, gender, hypertension, energy intake or smoking status, the multiple logistic regression model found that the multivariable adjusted OR was 0.610 (95% CI 0.428-0.870) for
the highest level of vitamin C intake (>154.78 mg/d) in comparison with the lowest level (≤ 63.26 mg/d). The results suggested that the vitamin C intake was inversely associated with the Type 2 diabetes (r=-0.029, P<0.05).
CONCLUSION:There is a significant negative correlation between the dietary vitamin C intake and the risk of Type 2 diabetes.
