Functional Cell Receptors for Human Coronavirus
10.3760/cma.j.issn.1009-9158.2010.0005
- VernacularTitle: 人类冠状病毒功能性细胞受体
- Author:
Li YAN
1
;
Jie XIANG
1
;
Tianpen CUI
1
Author Information
1. Grade 2019 Clinical Laboratory Diagnostics, School of Laboratory Medicine, Hubei University ofChinese Medicine, Wuhan 430065,China
- Publication Type:Journal Article
- Keywords:
Coronavirus;
Peptidyl-dipeptidase A;
Receptors, Cell Surface;
Receptors, Virus
- From:
Chinese Journal of Laboratory Medicine
2020;43(0):E005-E005
- CountryChina
- Language:Chinese
-
Abstract:
Viruses infect host cells by binding to receptors on thesurface of cells. Receptor is an important factor affecting host range and interspecific transmission. In December 2019, an outbreak of unexplained pneumonia occurred in Wuhan, Hubei province. The pathogen was a new coronavirus, named 2019 NovelCoronavirus (2019-nCoV) by WHO. Angiotensin-converting enzyme 2 (ACE2) was found to be the receptor of 2019-nCoV.This review provides a brief overview of human coronavirus receptors and their applications, with a view to providing references for the tracing, cross-species transmission, epidemiological analysis and antiviral and vaccine studies of 2019-nCoV.
