Research progression on triage of human papillomavirus positive women
10.3760/cma.j.issn.0253-3766.2018.09.001
- VernacularTitle: 高危型人乳头状瘤病毒感染人群分流方法的研究进展
- Author:
Juxiao LI
1
;
Li DONG
2
;
Li LI
3
;
Wen CHENG
1
Author Information
1. Department of epidemiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
2. Institute of Biomedical Science, Shanxi University, Taiyuan 030006, China
3. Department of Public Health, Xinjiang University, Urumchi 830054, China
- Publication Type:Review
- Keywords:
Cervical neoplasms;
High risk human papillomavirus;
Biological markers;
Triage
- From:
Chinese Journal of Oncology
2018;40(9):641-646
- CountryChina
- Language:Chinese
-
Abstract:
Persistently high risk human papillomavirus (HPV) infection is one of the indispensable factors of cervical cancer, which is the secondly most common cancer of women in developing countries. Nowadays HPV DNA detection has been more frequently used in cervical cancer initial screening. However, the specificity and sensitivity of HPV DNA detection are low and the triage of HPV positive women is necessary to identify the authentically high-risk population, and avoid the waste of health care resource and excessive treatment. There are different advantages and disadvantages in triage methods including the cytology, HPV DNA genotype, HPV mRNA detection and biological markers such as p16/Ki-67, respectively. Here we briefly describe and evaluate each triage method.
