The molecularly etiological study on the GII.17 norovirus causing an acute gastroenteritis outbreak in Shenyang
10.3760/cma.j.issn.1003-9279.2017.03.006
- VernacularTitle: 我国沈阳一起GII.17型诺如病毒胃肠炎暴发的分子病原学特征研究
- Author:
Bing WANG
1
;
Chunqing ZHANG
1
;
Ping WANG
1
;
Meimei ZHANG
2
;
Zhiyong LIAN
1
Author Information
1. Shenyang Center for Disease Control and Prevention, Shenyang 110031, China
2. Liaoning Center for Disease Control and Prevention, Shenyang 110005, China
- Publication Type:Journal Article
- Keywords:
Norovirus;
Acute gastroenteritis;
Outbreak;
GII.17 genotype
- From:
Chinese Journal of Experimental and Clinical Virology
2017;31(3):208-211
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To define the etiology and genetics of the pathogen causing an acute gastroenteritis outbreak in a college of Shenyang.
Methods:A total of 15 anal swab samples were collected from students or kitchen staffs of the college where outbroke the epidemic of acute gastroenteritis in December 2015 in Shenyang, Liaoning province. Real-time PCR was performed to identify the infection of Norovirus(NoV). The NoV genes were amplified and sequenced for those positive samples, followed to perform phylogenetic analysis.
Results:Of the 15 specimens, 12 were NoV positive by Real-time PCR, phylogenetic analysis showed that the infected virus of the outbreak was belonged to NoV genotype GII.17. The homology between the present virus and new mutated GII.17 strain of KR020503 identified in 2014—2015 epidemic outbreak in China was over 99%.
Conclusions:The new mutated NoV GII.17 caused the acute gastroenteritis outbreak in a college of Shenyang in 2015, NoV GII.17 was detected firstly in Northeast China.
