Research hotspots and progress of hepatic fibrosis – 2019 viewpoints
10.3760/cma.j.issn.1007-3418.2019.06.001
- VernacularTitle: 肝纤维化研究热点及进展—2019年视点
- Author:
Jinsheng GUO
1
Author Information
1. Division of Digestive Diseases, Zhongshan Hospital, Shanghai Institute of Liver Diseases, Fudan University, Shanghai 200032, China
- Publication Type:Editorial
- Keywords:
Liver fibrosis;
Molecular mechanisms;
Diagnosis;
Treatment
- From:
Chinese Journal of Hepatology
2019;27(6):401-402
- CountryChina
- Language:Chinese
-
Abstract:
The application of modern bioinformatics, 'omics’ and molecular biology to research of fibrotic liver diseases holds promise to accelerate the development of new therapeutic targets and therapies for hepatic fibrosis. Specifically, progress is anticipated in delineating pathways of fibrosis reversal and functional compensation, and defining key determinants and presenting factors associated with fibrosis progression and reversion. These efforts will also lead to develop accurate biomarkers and methods for early noninvasive diagnosis, and to accelerate the testing of anti-fibrotic drugs.