Research Progress on Hierarchical Structure of Cortical Bone and Its Toughening Mechanisms
10.16156/j.1004-7220.2018.03.14
- VernacularTitle:皮质骨的多级结构与韧化机制研究进展
- Author:
Can XU
1
;
Mingqing LI
1
;
Chenggong WANG
1
;
Kanghua LI
2
;
Hua LIU
1
Author Information
1. Department of Foot and Ankle Surgery, Department of Orthopedics, Xiangya Hospital,Central South University
2. Institute of Orthopedics, Central South University
- Publication Type:Journal Article
- Keywords:
cortical bone;
hierarchical structure;
intrinsic toughening;
extrinsic toughening;
toughening mechanism;
biomechanics
- From:
Journal of Medical Biomechanics
2018;33(3):E273-E279
- CountryChina
- Language:Chinese
-
Abstract:
Cortical bone is a kind of natural biological composite materials, which is mainly composed of tropocollagen molecules and nanoscale hydroxyapatite mineral crystals. It possesses high strength, stiffness and fracture toughness and has the ability to tolerate damage and self-heal. In the long process of evolution, bone tissues form the biomechanical strength and toughness to meet its functional needs. The excellent mechanical properties of cortical bone are closely related to its hierarchical microstructure. This paper reviewed the hierarchical microstructure of cortical bone and its toughening mechanisms, which would contribute to understanding the diagnosis, prevention and treatment of aging-related osteoporosis and the pathological mechanism of bone diseases.
