Diagnosis and treatment of non-alcoholic fatty liver disease in children
10.3760/cma.j.issn.2095-428X.2019.19.001
- VernacularTitle: 儿童非酒精性脂肪性肝病的诊治进展
- Author:
Jie WU
1
;
Mei SUN
Author Information
1. Department of Pediatric Gastroenterology, Shengjing Hospital of China Medical University, Shenyang 110004, China
- Publication Type:Journal Article
- Keywords:
Non-alcoholic fatty liver disease;
Diagnosis;
Treatment;
Child
- From:
Chinese Journal of Applied Clinical Pediatrics
2019;34(19):1441-1444
- CountryChina
- Language:Chinese
-
Abstract:
Non-alcoholic fatty liver disease (NAFLD) is a chronic steatosis of the liver in children and adolescents under 18 years of age.It is closely related to insulin resistance and genetic susceptibility.Its clinical symptoms are often non-specific.Diagnosis mainly depends on imaging findings and laboratory tests.Liver biopsy is the " golden standard" , but it is not a routine approach because of its traumatic nature.NAFLD in children should be distinguished from other hereditary metabolic diseases and liver diseases that can cause liver steatosis.At present, diet and exercise therapy are its first-line treatment.In addition, hepatoprotective therapy, improvement of insulin resistance and hyperlipidemia, vitamin E, probiotics are also gradually attracting attention.
