Research progress of less invasive surfactant application in premature infants with respiratory distress syndrome
10.3760/cma.j.issn.2095-428X.2019.16.021
- VernacularTitle: 侵入性较小的肺表面活性物质使用技术治疗早产儿呼吸窘迫综合征研究进展
- Author:
Junling MA
1
;
Chao NING
;
Xiuying TIAN
;
Jun ZHENG
Author Information
1. Department of Neonatology, Tianjin Central Hospital of Gynecology Obstetrics, Tianjin 300100, China
- Publication Type:Review
- Keywords:
Less invasive surfactant application;
Respiratory distress syndrome;
Pulmonary surfactant;
Endotracheal intubation;
Infant, premature;
Mechanical ventilation;
Serious complications
- From:
Chinese Journal of Applied Clinical Pediatrics
2019;34(16):1273-1276
- CountryChina
- Language:Chinese
-
Abstract:
Intratracheal surfactant administration is the only specific treatment for respiratory distress syndrome and usually requires endotracheal intubation, positive pressure and/or mechanical ventilation which are harmful to the immature lung.One of these alternative methods is less invasive surfactant application (LISA) via a thin endotracheal catheter during spontaneous breathing with continuous positive airway pressure.Use of LISA allows administration of surfactant while avoiding intubation and positive pressure.Observational studies have fostered expectations of a positive effect of LISA on serious complications of preterm infants and the need for mechanical ventilation.However, there is still a controversy about indications, premedication and serious complications of preterm infants while using LISA.This article reviews the controversies of LISA technology in preterm infants with respiratory distress syndrome.
