Research Progress in Structural Design of Porous Scaffolds and Implants Based on 3D Printing
10.16156/j.1004-7220.2019.04.17
- VernacularTitle:基于3D打印多孔支架和植入体的结构设计研究进展
- Author:
Chunling ZHAO
1
;
Shaowei JIA
1
;
Jian LI
2
;
Rui ZHANG
2
;
He GONG
3
Author Information
1. Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University
2. Beijing Key Laboratory of Rehabilitation Technical Aids for Old-Age Disability, Key Laboratory of Intelligent Control and Rehabilitation Technology of the Ministry of Civil Affairs, National Research Center for Rehabilitation Technical Aids
3. Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University;Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University
- Publication Type:Journal Article
- Keywords:
porous scaffold;
stress shield;
functionally graded structure;
three-dimensional (3D) printing;
implant
- From:
Journal of Medical Biomechanics
2019;34(4):E446-E452
- CountryChina
- Language:Chinese
-
Abstract:
The high elastic modulus of scaffolds or implants will result in stress shielding effect, which may lead to bone resorption and scaffold or implant loosening in the late stage. Porous scaffolds and implants can adjust their porosity and elastic modulus according to the mechanical environment, thereby reducing stress shielding; meanwhile, porous structures are beneficial to bone tissue growth, which is conducive to osseointegration. Three kinds of basic structure for porous scaffolds and implants by 3D printing were summarized, namely, uniform porous structure, bone-like trabecular structure and functionally graded structure. The design methods of these structures were introduced respectively, including computer-aided design (CAD)-based, implicit surface-based, image-based and topology optimization-based design method, so as to provide references for solving the stress shielding problem, as well as designing porous scaffolds and implants.