Chemical Compositions and Pharmacological Activities of Polygoni Multiflori Radix
10.13422/j.cnki.syfjx.20191212
- VernacularTitle: 何首乌化学成分与药理作用研究进展
- Author:
Hao WANG
1
;
Jian YANG
2
;
Liang-yun ZHOU
1
;
Bi LUO
1
;
Xuan-xuan CHENG
1
;
Chun-rong ZHANG
1
;
Xiao-min TANG
1
;
Li-ming PAN
1
;
Lu LIU
1
;
Quan YANG
1
Author Information
1. School of Traditional Chinese Medicine(TCM), Key Laboratory for Production & Development of Cantonese Medicinal Materials Under State Administration of TCM, Guangzhou Comprehensive Experimental Station Chinese Materia Medica Industry Technology System, Guangdong Provincial Research Center on Good Agricultural Practice & Comprehensive Agricultural Development Engineering Technology of Cantonese Medicinal Materials, Guangdong Pharmaceutical University, Guangzhou 510006, China
2. State Key Laboratory Breeding Base of Authentic Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China
- Publication Type:Research Article
- Keywords:
Polygoni Multiflori Radix;
chemical component;
pharmacological activities;
research advance
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2019;25(13):192-205
- CountryChina
- Language:Chinese
-
Abstract:
As a common tonic traditional Chinese medical herb,Polygoni Multiflori Radix has been extensively applied in clinic. In recent years,there have been many literatures related to Polygoni Multiflori Radix. By reviewing the literatures in domestic and foreign,the latest progress on chemical components and pharmacology of Polygoni Multiflori Radix have been summarized and analyzed. At present,more than 133 kinds of compounds have been isolated from Polygoni Multiflori Radix, such as stilbene glycosides,terpenoids,flavonoids,phospholipids and phenylpropanoids. Among them, stilbene dimer and dianthrone glycosides are two kind of new compounds recently isolated from it. The current researches about the pharmacological effect of Polygoni Multiflori Radix focus on anti-oxidative,anti-tumor,anti-atherosclerosis and neuro-protective effects,with potentials in treating neurodegenerative diseases, preventing and treating arterial and reducing blood sugar. Its medicinal ingredients mainly include stilbene glycosides,terpenoids and flavonoids,in which 2,3,5,4'-tetrahydroxysilbene 2-O-glucopyranoside shows a variety of biological activities. However,there are a few studies on the pharmacological activities of other compounds. Therefore,to ensure the further development and utilization of Polygoni Multiflori Radix,it is suggested to conduct a more in-depth and comprehensive research on the material basis of its efficacy.
