New Phenolic Glycoside from Aerial Part of Allium sativum
10.13422/j.cnki.syfjx.20192215
- VernacularTitle: 大蒜地上部分中1个新的酚苷类化合物
- Author:
Bin HU
1
;
Hai-xue KUANG
1
;
Yun-jie XIN
1
;
Qiu-hong WANG
1
Author Information
1. Heilongjiang Key Laboratory of Traditional Chinese Medicine(TCM) and Natural Medicine Pharmacodynamic Material Basis, Key Laboratory of Basis and Application Research of Northern Medicine under Ministry of Education, Heilongjiang University of Chinese Medicine, Harbin 150040, China
- Publication Type:Research Article
- Keywords:
Allium sativum;
aerial part;
phenolic glycosides;
dasuanxinoside J;
phytosterols
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2019;25(22):121-125
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical constituents from the aerial part of Allium sativum. Method: The aerial part of A. sativum was treated by heating reflux extraction with 70% ethanol. The combined extracting solution was treated with decompressed recovery solvent to obtain the total extract. The total extract's thick paste was suspended with an appropriate amount of distilled water, and then extracted with petroleum ether, ethyl acetate and water-saturated n-butyl alcohol to obtain petroleum ether extraction fraction, ethyl acetate extraction fraction and n-butyl alcohol extraction fraction. The n-butyl alcohol extraction fraction was isolated and purified by positive phase silica gel column chromatography, ODS column chromatography and preparative HPLC,etc. The structures of the chemical constituents were elucidated by means of physicochemical properties and spectroscopic analysis, and spectral data, like 1H-NMR, 13 C-NMR, DEPT, HMBC and HR-ESI-MS. Result: Seven compounds were isolated and identified as 2-methoxy-phenol-1-O-α-L-arabinopyranosyl-(1→6)-β-D-glucopyranoside(1),phenyl-ethanol-4-O-β-D-xylopyranosyl-(1→6)-β-D-glucopyranoside(2),trans-resveratrol 3-O-β-D-glucopyranoside(3),stigmasterol(4),β-sitosterol(5),stigmasterol-3-O-β-D-glucopyranoside(6) and daucosterol(7). Conclusion: Compound 1 is a new phenolic glycoside named dasuanxinoside J,and compounds 2-7 are isolated from A. sativum for the first time.
