Interpretation of Prescription and Syndrome of Yangjing Zhongyu Tang and Its Modern Research Progress
10.13422/j.cnki.syfjx.20191647
- VernacularTitle: 养精种玉汤的方证释义及现代研究进展
- Author:
Jun-ping ZHU
1
;
Jia-ming WEI
1
;
Rui-lian LIU
2
;
Hui-hui LIANG
1
;
Yan MAO
1
;
Wen WEN
1
;
Ge YU
1
;
Yi-qun ZHOU
1
;
Fu-yuan HE
1
;
Wen-long LIU
1
;
Xi-li ZHANG
1
Author Information
1. College of Pharmacy, Hunan Provincial Key Laboratory of Druggability and Preparation Modification for Traditional Chinese Medicine(TCM), Laboratory of Supramolecular Mechanism and Mathematic-Physics Chracterization for Chinese Materia Medica, Hunan University of Chinese Medicine, Changsha 410208, China
2. Hunan Academy of Chinese Medicine, Changsha 410006, China
- Publication Type:Research Article
- Keywords:
famous classical formulas;
Yangjing Zhongyu Tang;
supramolecular chemistry;
interpretation of prescription and syndrome;
pharmacological research;
clinical research;
quality standard;
druggability
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2019;25(23):209-214
- CountryChina
- Language:Chinese
-
Abstract:
Yangjing Zhongyu Tang, from FU Qing-zhu Nvke, is a famous classical formula of clinical value for treating blood deficiency syndrome of female infertility in the Qing dynasty. The prescription seems plain, but it is rigorous and effective with high research value. In this paper, the ancient books and modern documents of Yangjing Zhongyu Tang were analyzed from the aspects of traceability of Chinese materia medica in the formula, pharmacological research, clinical research, etc. It could be concluded that the pharmacological studies of this formula were mostly to investigate the mechanism and efficacy of its treatment for infertility, but there was a lack of comprehensive interpretation of the structure, function and principle of pharmacodynamic substance in this formula. In this paper, combined with the contents of supramolecular imprinting template and network pharmacology, the new direction of pharmacological research of Chinese medicine compound was put forward. Quality control of Yangjing Zhongyu Tang mostly based on small molecule compounds, so it was suggested to break the inherent thinking, and increase the detection of macromolecule compounds and supramolecular of Chinese materia medica. The druggability of this formula involved in the preliminary study of decoctions, plasters and granules. Considering the quality stability of Chinese materia medica in the formula and the scientificity of druggability of this formula, the compatibility principle of traditional Chinese medicine (TCM) and modern supramolecular chemistry theory could be combined to study the change law of druggability of TCM before and after compatibility, so as to provide new reference materials for the follow-up clinical application and development of Yangjing Zhongyu Tang.
