Clinical Efficacy by Kidney Tonifying and Essence Strengthening Method in Regulating Pulse Wave Velocity to Delay Physiological Vascular Aging
10.13422/j.cnki.syfjx.20191723
- VernacularTitle: 补益肾精法调节脉搏波速度延缓生理性血管老化的临床观察
- Author:
Zheng-yu LU
1
;
Yun GU
2
;
Shui-miao LIN
3
;
Zhao-yun XIA
1
;
Lu-qian PAN
2
Author Information
1. Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine(TCM), Shanghai 200437, China
2. Longhua Hospital Affiliated to Shanghai University of TCM, Shanghai 200032, China
3. Shanghai Institute of Geriatrics of TCM, Shanghai 200031, China
- Publication Type:Research Article
- Keywords:
senility;
vascular aging;
traditional Chinese medicine;
kidney tonifying and essence strengthening method
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2019;25(23):93-97
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe the clinical efficacy of kidney tonifying and essence strengthening method in delaying physiological vascular aging. Method: Sixty-two subjects who completed the study were randomly divided into experimental group (31 cases) and control group (31 cases) with the matching research method. The experimental group was treated with kidney tonifying and essence strengthening recipe orally for 24 weeks, while the control group was not interfered with traditional Chinese medicine (TCM). Score of TCM syndrome in kidney deficiency syndrome, pulse wave velocity, intima-media thickness, plasma homocysteine level and serum superoxide dismutase level were evaluated before and after treatment. Result: Compared with before treatment period, the score of TCM syndrome in kidney deficiency syndrome, pulse wave velocity and plasma homocystenine level decreased, while the serum superoxide dismutase level increased in the experimental group after treatment (P<0.01). The score of TCM syndrome in kidney deficiency syndrome, pulse wave velocity, intima-media thickness and plasma homocysteine level increased, while the serum superoxide dismutase level decreased in control group after treatment (P<0.05, P<0.01). After treatment, the score of TCM syndrome in kidney deficiency syndrome in experimental group was lower than that in control group (P<0.01), and the serum superoxide dismutase level in experimental group was higher than that in control group (P<0.01). Conclusion: The kidney tonifying and essence strengthening method may delay the aging of physiological blood vessels caused by aging.
