Progress in treatment of acute aluminum phosphide poisoning
10.3760/cma.j.issn.1001-9391.2019.11.021
- VernacularTitle: 急性磷化铝中毒的治疗进展
- Author:
Mingfeng LU
1
;
Shinan NIE
2
Author Information
1. Department of Emergency Medicine, General Hospital of Eastern Theater Command, Nanjing 210002, China; Department of Emergency Medicine, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou 225000, China
2. Department of Emergency Medicine, General Hospital of Eastern Theater Command, Nanjing 210002, China
- Publication Type:Review
- Keywords:
Aluminum phosphide;
Phosphine;
Poisoning;
Treatment
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2019;37(11):877-880,封三
- CountryChina
- Language:Chinese
-
Abstract:
Aluminum phosphide (ALP) is frequently used for grain conservation despite its high toxicity. In some developing countries increased utilization of ALP has resulted in increment of ALP-attributed poisoning numbers. The mortality of ALP poisoning is extremely high and no effective antidote is available so far. However, the astute survey of potential misconceptions in the course of acute toxicity has led some scientists to introduce novel therapeutic approaches. Meanwhile, some new antioxidants were discovered and expected to be used in the management of ALP poisoning. In addition, the progress in intensive care has promoted technologies such as CRRT, IABP and ECMO for the treatment of ALP poisoning with reported success in alleviating severe toxicity. Recent studies on the therapy of ALP poisoning are reviewed in this article.
