Analysis of traditional Chinese medicine treatment of asthma from different syndrome based on literature
10.3760/cma.j.issn.1673-4246.2019.12.019
- VernacularTitle: 基于文献的中医治疗哮喘辨证用药规律分析
- Author:
Nong TANG
1
;
Zongyou LI
2
;
Li KANG
3
;
Shuo YANG
4
;
Lei LEI
3
Author Information
1. Guangxi University of Chinese Medicine, Nanning 530299, China
2. Institute of Information on Traditional Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China
3. Traditional Chinese Medicine Information Technology Research Office, Institute of Information on Traditional Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China
4. Scientific Research and Education Department, Institute of Information on Traditional Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China
- Publication Type:Journal Article
- Keywords:
Asthma;
Formula composing rules;
Frequent item sets;
Co-occurrence matrix;
Prescription for new drugs;
Data mining
- From:
International Journal of Traditional Chinese Medicine
2019;41(12):1370-1374
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the rules of TCM treatment of Asthma on different syndromes.
Methods:We searched the modern clinical literature of asthma treated by TCM form Chinese Clinical Literature Database, SinoMed, CNKI, Wanfang Database and CQVIP from 1949-2017, collected key information such as diseases, syndromes, and drug composition by human-computer integration and constructed a database. We calculated the co-occurrence matrix of syndrome-herb and the frequent item sets of herb for different syndromes using TCM Miner (http://tcmminer.cintcm.com:8023/tcm/index.jsp). The prescription and treatment of asthma with different syndrome were analyzed, and a new medicine prescription was proposed for common five kinds of common syndromes.
Results:There were 234 articles containing 124 syllables, 1 337 prescriptions and 290 herbs. For different syndromes, the high-frequency medicine was obviously different, which reflected the important ideas of TCM syndrome differentiation. According to five common syndromes including fever syndrome, cold syndrome, lung-spleen qi deficiency syndrome and kidney-yang deficiency syndrome, five new drug prescriptions have evolved.
Conclusions:Analysis of TCM prescriptions based on differentiating syndromes can explore the essence of TCM and provided ideas and data support for researchers.