Quality control of pre-analytical processes for ctDNA analysis
10.3760/cma.j.issn.1009-9158.2020.02.005
- VernacularTitle: 重视ctDNA检测的分析前质量控制
- Author:
Wei GUO
1
Author Information
1. Department of Clinical Laboratory, Zhongshan Hospital Fudan University, Shanghai 200032, China
- Publication Type:Journal Article
- Keywords:
Circulating tumor DNA;
Clinical laboratory techniques;
Quality control
- From:
Chinese Journal of Laboratory Medicine
2020;43(2):120-123
- CountryChina
- Language:Chinese
-
Abstract:
With the development of precision oncology, a large number of clinical studies have confirmed the great potential of ctDNA in tumor management. However, the effectiveness and versatility of ctDNA detection are still questioned, which hinder the realization of clinical application of ctDNA detection, so there is an urgent need to develop unified quality control standards. The standardized pre-analytical processes for ctDNA analysis are the prerequisite to ensure the subsequent molecular detection. This paper will focus on the factors of quality control of pre-analytical processes for ctDNA analysis, in order to promote the standardized management of ctDNA detection.
