How far is the clinical application of EVs-based tumor diagnosis?
10.3760/cma.j.issn.1009-9158.2020.02.004
- VernacularTitle: 基于EVs的肿瘤诊断，距离真正的临床应用还有多远
- Author:
Yanjun DIAO
1
;
Liu YANG
;
Xiaoke HAO
Author Information
1. Department of Clinical Laboratory Medicine, Xijing Hospital, Air Force Military Medical University, Xi′an 710032, China
- Publication Type:Journal Article
- Keywords:
Extracellular vesicles;
Biomarkers, tumor;
Early detection of cancer
- From:
Chinese Journal of Laboratory Medicine
2020;43(2):115-119
- CountryChina
- Language:Chinese
-
Abstract:
As a new type of paracrine/autocrine and remote signaling, extracellular vesicles (EVs) involved in almost the whole process of tumorigenesis, progression, metastasis, and drug resistance, which has greatly inspired tumor diagnosis and treatment. EVs have the great potential to be the blood or urine biomarkers and can be used for cancer diagnosis, prognosis and monitoring. Due to its great clinical application value, EVs have become a hotspot in cancer research in recent years. Therefore, in this review, the advantages, progression, and technical challenges of EVs biomarkers in clinical tumors diagnosis are discussed.
