Research progress of 6-18Ffluoro-L-dopa PET/CT imaging
10.3760/cma.j.issn.2095-2848.2020.02.012
- VernacularTitle: 18F-DOPA PET/CT显像的研究进展
- Author:
Jingnan WANG
1
;
Yaping LUO
;
Li HUO
;
Fang LI
Author Information
1. Department of Nuclear Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences; Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Beijing 100730, China
- Publication Type:Review
- Keywords:
Levodopa;
Fluorine radioisotopes;
Positron-emission tomography;
Tomography, X-ray computed;
Trends
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2020;40(2):113-117
- CountryChina
- Language:Chinese
-
Abstract:
6-[18F]fluoro-L-dopa (18F-DOPA) is a levodopa analogue. 18F-DOPA PET/CT imaging is considered as an ideal tool in the diagnosis and evaluation of Parkinson′s disease, brain tumors, pheochromocytoma/paraganglioma, neuroblastoma, gastrointestinal carcinoid, medullary thyroid cancer and congenital hyperinsulinemia. This paper reviews the synthesis, mechanism of localization, imaging procedures, clinical indications and research advances of 18F-DOPA.
