The 473rd case: renal failure, abdominal pain, and mental abnormality

VernacularTitle: 第473例——肾衰竭，腹痛，神志异常
Author: Gang CHEN ¹ ; Limeng CHEN ; Xuemei LI
Author Information

1. Department of Nephrology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China
Publication Type:Journal Article
Keywords: Renal artery stenosis; Renal failure; Peritoneal dialysis; Wernick-Korsakoff syndrome
From: Chinese Journal of Internal Medicine 2020;59(1):82-85
CountryChina
Language:Chinese
Abstract: A 43-year-old male presented with elevated serum creatinine for 4 years and developed abdominal pain for 3 days. He started peritoneal dialysis 2 months ago. Dialysis-related peritonitis was ruled out and acute gastroenteritis was diagnosed. The patient was administrated with ertapenem 500 mg/d. An acute mental abnormality developed 3 days later. After excluded organic encephalopathy, ertapenem was discontinued for the suspicion of antibiotic-related encephalopathy. The frequency of peritoneal dialysis was increased to accelerate the clearance of antibiotics. However, the metal abnormality became even more severe. Then a diagnosis of Wernick-Korsakoff syndrome was considered. After the administration of high dose vitamin B₁, the mental disorder dramatically relieved. Vitamin B₁ 30 mg/d is maintained during peritoneal dialysis and the mental disorder does not relapse.