Application and Research Progress of UPLC in Analysis of Traditional Chinese Medicine and Its Compound
10.13422/j.cnki.syfjx.20182004
- VernacularTitle: UPLC在中药及其复方分析中的应用和研究进展
- Author:
Qing ZHANG
1
;
Qiu-yue LUO
1
;
Jing LI
1
;
Xu-feng PU
2
Author Information
1. College Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611130, China
2. Chengdu Institute for Food and Drug Control, Chengdu 610045, China
- Publication Type:Research Article
- Keywords:
ultra-high performance liquid chromatography (UPLC);
component analysis;
fingerprints;
metabolomics;
UPLC-mass spectrometry;
formula;
principal component analysis
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2019;25(3):226-234
- CountryChina
- Language:Chinese
-
Abstract:
Ultra-high performance liquid chromatography(UPLC) is a new liquid chromatography technology,which developed on the basis of high performance liquid chromatography(HPLC).It has the characteristics of super high efficiency,high separation degree and high sensitivity,and has been widely used in the analysis of components in traditional Chinese medicine,the studies on metabolomics,establishment of fingerprint chromatogram,determination of unknown compounds combined with mass spectrometry and other detectors,etc.In this paper,the authors reviewed the application of UPLC in the field of traditional Chinese medicine through a review of the literature in the past 5 years,and summed up its relative advantages and development prospects,in order to provide scientific guidance and basis for pharmaceutical workers to make better use of UPLC technology.
