Effect of Heat Treatment on Contents of Sulfur Dioxide Residue and Sulfur-containing Derivatives in Sulfur-fumigated Codonopsis Radix
10.13422/j.cnki.syfjx.20182414
- VernacularTitle: 热处理脱硫对硫熏党参中二氧化硫残留及含硫衍生物的影响
- Author:
Fei XU
1
;
Ming KONG
2
;
Jin-di XU
3
;
Song-lin LI
2
;
Yan JIANG
1
Author Information
1. College of Chemical Engineering, Nanjing Forestry University, Nanjing 210037, China
2. Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Nanjing University of Chinese Medicine, Nanjing 210028, China
3. Jiangsu Province Academy of Traditional Chinese Medicine & Jiangsu Branch of Chinese Academy of Chinese Medical Sciences, Nanjing 210028, China
- Publication Type:Research Article
- Keywords:
Codonopsis Radix;
sulfur-fumigation;
heat-treating de-sulfur method;
sulfur-containing derivatives
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2019;25(3):162-166
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To evaluate the feasibility of heat-treating de-sulfur method for sulfur-fumigated Codonopsis Radix (CR) by investigating the changes in contents of sulfur dioxide residue and sulfur-containing derivatives after sulfur-fumigation.Method: Qualitative and semi-quantitative characterization of sulfur-containing derivatives was analyzed by ultra-performance liquid chromatography-quadrupole-time of flight-mass spectrometry (UPLC-Q-TOF-MS/MS),and sulfur dioxide residues were determined by acid-base titration method. Then the correlations between sulfur dioxide residues and sulfur-containing derivatives in sulfur-fumigated CR samples with different sulfur-fumigation and heat treatment extents were analyzed.Result: Atractylenolide Ⅱ and atractylenolide Ⅲ sulfur-containing derivatives were identified as major characteristic markers of sulfur fumigated CR. With the increase of sulfur-fumigation time,the content of sulfur dioxide residues was continuously increased,while the content of sulfur-containing derivatives was elevated at the beginning and then reached to a plateau, so there was not necessarily a positive correlation between sulfur dioxide residue and the amount of sulfur derivatives. With the increase of heat-treated time,the content of sulfur dioxide residues was continuously decreased,while the content of sulfur-containing derivatives was decreased first and remained at a high level later. There was no clear correlation between sulfur dioxide residue and sulfur-containing derivatives in different sulfur-fumigated and heat-treating de-sulfur degrees of CR.Conclusion: Heat-treatment could decrease the content of sulfur dioxide residue,but the content of sulfur-containing derivatives still remained at a high level, so heat treatment could not reinstate the inner quality of sulfur-fumigated CR to its non-fumigated ones. Therefore, heat-treating de-sulfur is not a feasible method for the quality assurance of sulfur-fumigated CR.
