Relationship between recurrent benign paroxysmal positional vertigo and serum 25-hydroxyvitamin D in middle-aged and elderly patients
10.3760/cma.j.issn.1008-6706.2019.10.015
- VernacularTitle: 中老年人复发性良性阵发性位置性眩晕与血清25羟维生素D的关系
- Author:
Zhen HAO
1
;
Yi TAN
2
Author Information
1. Department of Respiratory Diseases, Quhua Hospital of Zhejiang Province, Quzhou, Zhejiang 324004, China
2. Department of Neurology, Quhua Hospital of Zhejiang Province, Quzhou, Zhejiang 324004, China
- Publication Type:Journal Article
- Keywords:
Vertigo;
25-Hydroxyvitamin D;
Bone density;
Middle aged;
Aged
- From:
Chinese Journal of Primary Medicine and Pharmacy
2019;26(10):1213-1216
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the correlation between serum 25-hydroxyvitamin D (25-OHD) and benign paroxysmal positional vertigo(BPPV) in middle-aged and elderly patients.
Methods:From October 2015 to October 2016, 250 middle-aged and elderly patients with idiopathic BPPV in Quhua Hospital of Zhejiang Province were selected in the research.According to whether the patients relapsed, the patients were divided into recurrence group(120 cases) and non-recurrent group(130 cases). And 100 healthy subjects who were examined in our hospital during the same period were selected as the healthy control group(control group). The serum 25-OHD levels and bone mineral density(BMD) were compared.The DHI scores of the three groups were scored and compared.Then, the correlation between 25-OHD, osteoporosis and DHI score and BPPV was analyzed.
Results:The levels of serum 25-OHD in the control group, non-relapse group and recurrence group were (35.12±3.95)μg/L, (21.62±4.32)μg/L and (16.25±3.86)μg/L, respectively, there were statistically significant differences among the three groups (F=4.567, P<0.05). The BMD in thecontrol group, non-relapsed group and recurrence group were (0.97±0.61), (-1.24±0.19), (-2.62±0.37), respectively, and the difference was statistically significant (F=6.478, P<0.05). The DHI scores in the control group, non-relapsed group and relapsed group were (4.62±3.15)points, (35.26±12.54)points, (53.28±11.68)points, respectively, there were statistically significant differences among the three groups (F=6.231, P<0.05). Regression analysis showed that the severity of BPPV in middle-aged and elderly patients was negatively correlated with 25-OHD level(r=-0.367, P<0.05).
Conclusion:The level of 25-OHD is negatively correlated with the severity of BPPV in middle-aged and elderly patients.
