Research progress on blood pressure regulation disorder in Parkinson′s disease
10.3760/cma.j.issn.1006-7876.2019.10.010
- VernacularTitle: 帕金森病血压调节障碍的研究进展
- Author:
Yansheng DU
1
;
Yuan ZHANG
2
;
Qingbo ZHOU
1
Author Information
1. Department of Neurology, the Second Hospital of Shandong University, Jinan 250033, China
2. Center of Eidence-based Medicine, the Second Hospital of Shandong University, Jinan 250033, China
- Publication Type:Review
- Keywords:
Parkinson disease;
Orthostatic hypotension;
Supine hypertension;
Postprandial hypotension
- From:
Chinese Journal of Neurology
2019;52(10):847-851
- CountryChina
- Language:Chinese
-
Abstract:
Parkinson′s disease (PD) is the second most common neurodegenerative disease following Alzheimer′s disease, including motor and non-motor symptoms. Non-motor symptoms are mainly autonomic nervous dysfunction, which occur about 5-20 years earlier than motor symptoms. Abnormal blood pressure regulation is a common manifestation of autonomic nervous dysfunction. Long-term abnormal blood pressure can seriously hamper the quality of life and trigger deterioration of motor symptoms. Thus, it is necessary to obtain correct understanding of the etiology, mechanism, clinical features, diagnosis and treatment of PD with blood pressure regulation disorders in order to reduce the mortality rate and the burden of medical health. This article reviews the influencing factors, characteristics, mechanisms and management of PD with blood pressure regulation disorder.
