Application of microfluidic technology in detection of circulating tumor cells
10.3760/cma.j.issn.1009-8158.2019.10.004
- VernacularTitle: 微流控技术在循环肿瘤细胞检测领域的应用
- Author:
Taoye ZHANG
1
;
Wei LIU
1
Author Information
1. School of Physical Science and Technology, Wuhan University, Wuhan 430072, China
- Publication Type:Journal Article
- Keywords:
Neoplastic cells, circulating;
Microfluidics;
Microfluidic analytical techniques
- From:
Chinese Journal of Laboratory Medicine
2019;42(10):831-835
- CountryChina
- Language:Chinese
-
Abstract:
The early diagnosis of cancer is aimed at intervention, as far as possible in the early stage of the treatment of cancer, thereby reducing the suffering and economic burden of the patient. Circulating tumor cells (CTCs) are tumor cells that fall from the malignant tumor into the circulatory system and form cancer metastasis when they migrate to distant organs. The detection and identification of CTCs is important for the study, monitoring and intervention of cancer metastasis processes. However, the amount of CTCs in the blood is extremely rare, and the environment in the blood is complex, which poses a huge technical challenge for its screening and analysis. Various methods have been developed to enrich CTCs from blood samples of cancer patients. Among them, microfluidic technology has great advantages in the field of CTC detection.
