Prevalence of HIV, syphilis and HCV and their risk factors among drug users in Hangzhou
10.19485/j.cnki.issn2096-5087.2018.03.008
- VernacularTitle:杭州市吸毒人群艾滋病、 梅毒和丙肝感染状况及影响因素分析
- Author:
Jie JIN
1
;
Yan LUO
;
Jun-Fang CHEN
;
Xi-Ting LI
;
Xing-Liang ZHANG
;
Ke XU
Author Information
1. 杭州市疾病预防控制中心艾滋病性病防制所
- Keywords:
Drug users;
AIDS;
Syphilis;
HCV;
Related risk factors
- From:
Journal of Preventive Medicine
2018;30(3):248-252,256
- CountryChina
- Language:Chinese
-
Abstract:
Objective To learn the prevalence of HIV, syphilis and HCV and to identify the potential risk factors among drug users in Hangzhou. Methods A consecutive cross-sectional survey was conducted from 2012 to 2016. The drug users from compulsory rehabilitation center, community and methadone clinic were interviewed face to face with questionnaires to collect the information about their demographic characteristics, drug use behaviors and sexual behaviors. Blood specimens were collected for HIV, syphilis and HCV testing. Results Totally 4067 drug users were included during this 5-year study. The infection rates of HIV, syphilis and HCV were 0.64％, 7.25％ and 22.69％, respectively. Multivariate logistic regression analysis indicated that the risk factors for syphilis infection were female (OR=4.411, 95％ CI: 3.273-5.945) , single (married/cohabited:OR=0.664, 95％ CI: 0.482-0.915; divorced/widowed: OR=0.534, 95％ CI: 0.353-0.810) , club drug user (OR=5.064, 95％CI: 3.287-7.803) and mixed drug user (OR=2.663, 95％CI: 1.191-5.954); the risk factors for HCV infection were age (OR: 2.168-2.878), place of domicile (OR=1.747, 95％CI: 1.398-2.184), injecting drug use (OR=3.120, 95％CI: 2.534-3.840) and conventional drug use (club drug user: OR=0.348, 95％CI: 0.277-0.438; mixed drug user: OR=0.611, 95％CI: 0.390-0.959) . Conclusion The infection rate of syphilis and HIV is high among drug users in Hangzhou. Female, single, club drug use and mixed drug use may increase the risk of syphilis infection. high age, drug injection and migrant population are risk factors for HCV infection.
