Lox-1, a new target in cardiovascular disease
10.3969/j.issn.1006-0111.2014.05.001
- VernacularTitle:Lox-1--心血管疾病防治的新靶标
- Author:
Qian LI
1
;
Yaocheng RUI
Author Information
1. 第二军医大学药学院药理学教研室
- Keywords:
lectin-like oxidized low-density-lipoprotein receptor-1;
atherosclerosis;
oxidized low-density lipoprotein
- From:
Journal of Pharmaceutical Practice
2014;(5):321-323
- CountryChina
- Language:Chinese
-
Abstract:
Objective Lox-1 ( lectin-like oxidized low-density lipoprotein receptor-1 ) was one of the main receptor of ox-LDL, which took an important role in vascular endothelial dysfunction , the formation of foam cells , and the stability of atherosclerotic plaques .To investigate the role of Lox-1 in cardiovascular diseases .Methods The literatures of Lox-1 in cardiovascular diseases retro-spectively were reviewed .Results As a new ox-LDL scavenger receptor , Lox-1 played an important role in cardiovascular diseases . Conclusion Lox-1 might provide new ideas for cardiovascular diseases .
