A new alkaloid from <italic>Alstonia yunnanensis</italic>

VernacularTitle:鸡骨常山中的一个新生物碱
Author: Cui-jie WEI ¹ ; Jing XIE ¹ ; Zi-wei LI ¹ ; Jian ZHANG ¹ ; Xiao-qi ZHANG ¹ ; Wen-cai YE ¹
Author Information

1. Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, China; Guangdong Engineering Research Center for Modenization of TCM, Jinan University, Guangzhou 510632, China
Publication Type:Research Article
Keywords: Apocynaceae; italic>Alstonia yunnanensis; alkaloids; italic>N₄-methylpseudoakuammigine
From: Acta Pharmaceutica Sinica 2020;55(2):294-297
CountryChina
Language:Chinese
Abstract: Four alkaloids were isolated from the total alkaloids of the twigs and leaves of Alstonia yunnanensis (Apocynaceae) by using silica gel, ODS, Sephadex LH-20, and HPLC chromatography. Structures were determined by physical, chemical and spectroscopic methods and identified as N₄-methylpseudoakuammigine (1), pseudoakuammigine (2), vinorine (3), picraline (4). Among them, compound 1 is a new monoterpenoid indole alkaloid.