Infectious Diseases of the Stomach in Immune-compromised Patients
10.7704/kjhugr.2019.19.1.38
- Author:
Sang Min LEE
1
;
Dae Young CHEUNG
Author Information
1. Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. adagio@catholic.ac.kr
- Publication Type:Review
- Keywords:
Immune-compromised;
Infection;
Stomach
- MeSH:
Aspergillosis;
Autoimmune Diseases;
Bacteria;
Colitis;
Colon;
Communicable Diseases;
Cryptosporidium;
Cytomegalovirus Infections;
Esophagitis;
Esophagus;
Gastrointestinal Tract;
Helicobacter pylori;
Histoplasmosis;
HIV;
Humans;
Leishmaniasis;
Microbiota;
Mycobacterium avium Complex;
Opportunistic Infections;
Organ Transplantation;
Parasites;
Stomach;
Transplants;
Treponema
- From:The Korean Journal of Helicobacter and Upper Gastrointestinal Research
2019;19(1):38-41
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The gastrointestinal tract is a vast reservoir for internal microbiota; it is exposed directly to various externally introduced microbes, including bacteria, viruses, parasites and others. In immune-compromised conditions, the gastrointestinal tract is frequently affected by infectious diseases that seldom manifest clinically in immune-competent hosts. Immune-compromised conditions result from a variety of reasons, including human immunodeficiency virus infection, anti-cancer chemo-radiotherapy, immune suppressive therapy for autoimmune diseases, and organ transplantations. The stomach is a relatively rare site for opportunistic infections in immune-compromised patients compared to the esophagus and colon, where esophagitis and colitis develop frequently and cause significant clinical consequences. Helicobacter pylori infection is majorly involved in gastric malfunctioning in immune-compromised patients, followed by cytomegalovirus infection. Infections by Cryptosporidium, Mycobacterium avium complex, histoplasmosis, leishmaniasis, aspergillosis, or treponema, have been reported; however, gastric involvement of these agents is extremely rare. This review discusses the general aspects and recent reports on gastric infection in immune-compromised patients.
