Burden of Cirrhosis and Other Chronic Liver Diseases Caused by Specific Etiologies in China, 1990-2016: Findings from the Global Burden of Disease Study 2016.
- Author:
Man LI
1
;
Zhuo Qun WANG
2
;
Lu ZHANG
1
;
Hao ZHENG
3
;
Dian Wu LIU
1
;
Mai Geng ZHOU
2
Author Information
- Publication Type:Journal Article
- Keywords: China; Chronic liver disease; Cirrhosis; Epidemiology; Global burden of disease study
- From: Biomedical and Environmental Sciences 2020;33(1):1-10
- CountryChina
- Language:English
-
Abstract:
Objective:To estimate the burden of cirrhosis and other chronic liver diseases caused by specific etiologies in China.
Methods:Data from the Global Burden of Disease Study 2016 (GBD 2016) were used. We evaluated the burden by analyzing age-sex-province-specific prevalence, mortality, and disability-adjusted life-years (DALYs) of 33 provinces in China.
Results:From 1990 to 2016, prevalence cases in thousands increased by 73.7% from 6833.3 (95% : 6498.0-7180.6) to 11869.6 (95% : 11274.6-12504.7). Age-standardized mortality and DALY rates per 100,000 decreased by 51.2% and 53.3%, respectively. Male and elderly people (aged ≥ 60 years) preponderance were found for prevalence, mortality, and DALYs. The number of prevalence cases, deaths, and DALYs due to hepatitis C virus (HCV) increased by 86.6%, 8.7%, and 0.9%, respectively. Also, age-standardized prevalence rates decreased in 31 provinces, but increased in Yunnan and Shandong. The Socio-demographic Index (SDI) values were negatively correlated with age-standardized mortality and DALY rates by provinces in 2016; the correlation coefficients were -0.817 and -0.828, respectively.
Conclusion:Cirrhosis and other chronic liver diseases remain a huge health burden in China, with the increase of population and the aging of population. Hepatitis B virus (HBV) remains the leading cause of the health burden in China.
