Chemical constituents from Vernonia bockiana.
10.1016/S1875-5364(19)30114-1
- Author:
Shi-Hui DONG
1
;
Yan WU
2
;
Jian-Min YUE
3
Author Information
1. State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, China.
2. State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
3. State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China. Electronic address: jmyue@simm.ac.cn.
- Publication Type:Journal Article
- Keywords:
Sesquiterpenoid;
Steroid;
Vernonia bockiana
- From:
Chinese Journal of Natural Medicines (English Ed.)
2019;17(12):924-927
- CountryChina
- Language:English
-
Abstract:
A new sesquiterpenoid and two pregnane steroids, named vernobockolide C (1) and vernobockones A and B (2 and 3), respevtively, along with a known sesquiterpenoid, 7, 10-epoxy-11-hydroxy-bisabol-2-en-15-al, were isolated from the aerial part of Vernonia bockiana. Their structures were elucidated on the basis of extensive spectroscopic data analysis, especially 2D NMR (HSQC, HMBC, and ROESY). This study further expands the chemical space of this underexplored species.
