Three new secoiridoid glycosides from the flower buds of Lonicera japonica.
10.1016/S1875-5364(20)30006-6
- Author:
Ran YANG
1
;
Hao HAO
2
;
Jia LI
1
;
Jing XUAN
1
;
Ming-Feng XIA
2
;
Yong-Qing ZHANG
3
,
4
Author Information
1. Key laboratory of Natural Pharmaceutical Chemistry, Shandong University of Traditional Chinese Medicine, Jinan 250200, China.
2. Key laboratory of Pharmacology, Shandong University of Traditional Chinese Medicine, Jinan 250200, China.
3. Key laboratory of Natural Pharmaceutical Chemistry, Shandong University of Traditional Chinese Medicine, Jinan 250200, China. Electronic address: zyq622003@
4. com.
- Publication Type:Journal Article
- Keywords:
Anti-inflammatory activity;
Lonicera japonica;
Secoiridoid glycosides;
Spectroscopic analysis
- From:
Chinese Journal of Natural Medicines (English Ed.)
2020;18(1):70-74
- CountryChina
- Language:English
-
Abstract:
Three new secoiridoid glycosides, named lonijapoglycol A (1), aldosecolohanin C (2) and aldosecolohanin B (3), together with three known ones (4-6), have been isolated from the flower the buds of Lonicera japonica. All the structures were identified by spectroscopic analyses. Lonijapoglycol A (1) expressed significant anti-inflammatory activity to inhibit the release of β-glu-curonidase induced by platelet-activating factor in rat polymorphonuclear leukocytes with an IC value of 3.76 μmol·L.
