Research on antitumor active components and mechanisms of natural products
10.16438/j.0513-4870.2019-0669
- VernacularTitle:天然药物抗肿瘤活性成分及其作用机制研究进展
- Author:
Xiao-ping ZHANG
1
;
Jun-jing SHAO
2
;
Da-long MA
3
;
Fan LIU
2
;
Miao-miao LIU
2
;
Qing-hua CUI
2
Author Information
1. College of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China; Qingdao Academy of Chinese Medical Sciences, Shandong University of Traditional Chinese Medicine, Qingdao 266000, China; TCM Post-doctoral Research Center, Shandong University of Traditional Chinese Medicine, Jinan 250355, China
2. College of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China; Qingdao Academy of Chinese Medical Sciences, Shandong University of Traditional Chinese Medicine, Qingdao 266000, China
3. Department of Pharmacy, the Affiliated Hospital of Qingdao University, Qingdao 266005, China
- Publication Type:Research Article
- Keywords:
natural product;
antitumor;
active component;
mechanism
- From:
Acta Pharmaceutica Sinica
2019;54(11):1949-1957
- CountryChina
- Language:Chinese
-
Abstract:
Tumor, especially malignant tumor has become one of the major diseases, a serious threat to the health of people around the world. Modern clinical practice shows that the natural active products extracted from traditional Chinese medicine, marine medicine and other natural drugs, such as terpenes, alkaloids, polysaccharides, volatile oils and peptides, can effectively inhibit the growth of tumor cells. In this paper, the active components of natural antitumor products in recent years were summarized and their related mechanism was elucidated, so as to provide theoretical basis for the further development of natural antitumor drugs.
