Comparative study on quality of Scutellaria baicalensis Georgi in different harvest periods using UHPLC-MS/MS metabolomics technology
10.16438/j.0513-4870.2017-0466
- VernacularTitle:基于UHPLC-MS/MS代谢组学技术的不同采收期黄芩质量比较研究
- Author:
Yi-yuan PANG
1
;
Li-ying XUE
1
;
Yan-hong ZHENG
1
;
Yu-zhi ZHOU
1
;
Xue-mei QIN
1
;
Guan-hua DU
1
;
Xiang ZHANG
1
Author Information
1. Modern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan 030006, China
- Publication Type:ORIGINAL ARTICLES
- Keywords:
Scutellaria baicalensis Georgi;
UHPLC-MS/MS;
metabolomics;
harvest period
- From:
Acta Pharmaceutica Sinica
2017;52(12):1903-1909
- CountryChina
- Language:Chinese
-
Abstract:
The quality of Scutellaria baicalensis Georgi has a close relationship to the harvest time. With the annual and biennial Scutellaria baicalensis Georgi in different harvest periods as samples, we detected the dynamic changes of chemical compositions in their contents by UHPLC-MS/MS metabolomics technology, then identified the biomarkers of different harvest periods and analyzed their changes in content, finally analyzed the correlation among different metabolites. The results showed that chemical compositions of different harvest periods were obviously different, and showed regular changes. According to the results, if the flavonoid aglycones are chosen as the target components, the proposed harvest time could be May. If flavonoid glycosides, the time is from July to August. Plant metabolomics methodology based on UHPLC-MS/MS can be used to detect the chemical compositions of Scutellaria baicalensis Georgi in different harvest periods, which provide a reference to the optimum harvest period of Scutellaria baicalensis Georgi, and also provide a new method of quality evaluation of traditional Chinese medicinal materials.
