New triterpenoid saponins from the leaves of Panax notoginseng
10.16438/j.0513-4870.2017-0486
- VernacularTitle:三七叶中的新三萜皂苷
- Author:
Xin-yi LIU
1
;
Jie MA
1
;
Chuang-jun LI
1
;
Fang-you CHEN
1
;
Dong-ming ZHANG
1
Author Information
1. State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
- Publication Type:ORIGINAL ARTICLES
- Keywords:
Panax notoginseng;
chemical constituent;
triterpenoid saponins
- From:
Acta Pharmaceutica Sinica
2017;52(9):1432-1436
- CountryChina
- Language:Chinese
-
Abstract:
Five triterpene saponins were isolated from the aqueous extract of the leaves of Panax notoginseng (Burk.) F.H.Chen via various chromatographic approaches, including HPD-100 macroporous resin, silica gel, reverse phase C18 and so on. Spectroscopic and chemical methods were used to elucidated their structures, which were determined to be 3-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl-12β,23(R)-epoxydammara-24-ene-3β,6α,20(S)-triol 20-O-α-L-arabinofuranosyl-(1→6)-β-D-glucopyranoside (1), 3-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl-12β,23(R)-epoxydammara-24-ene-3β,6α,20(S)-triol 20-O-α-L-arabinopyranosyl-(1→6)-β-D-glucopyranoside (2), notoginsenoside FP2 (3), gypenoside Ⅸ (4), ginsenoside Rg1 (5). Compounds 1 and 2 are new compounds and named as notoginsenoside Fh8 and notoginsenoside Fh9.
