Progress of autophagy screening systems
10.16438/j.0513-4870.2015-0878
- VernacularTitle:自噬活性物质筛选系统研究进展
- Author:
Jing XIE
1
;
Xiao-wei ZHANG
1
;
Fang HUA
1
;
Zhuo-wei HU
1
Author Information
1. State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study, Institute of Meteria Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
- Publication Type:SPECIAL REPORTS
- Keywords:
autophagy;
autophagic flux;
autophagosome;
autolysosome;
autophagy screening system
- From:
Acta Pharmaceutica Sinica
2016;51(1):52-
- CountryChina
- Language:Chinese
-
Abstract:
Autophagy is an active research area in the biomedical field as its role has been identified in many physiological and pathological processes. Accordingly, there is a growing demand to identify, quantify and manipulate the process accurately. Meanwhile, there is great interest in identifying compounds that modulate autophagy because they may have applications in the treatment of a variety of autophagy-related diseases. In this review, we summarize the current status of autophagy screening systems to facilitate identification of autophagy modulators.
