Molecular markers of autophagy
10.16438/j.0513-4870.2015-0634
- VernacularTitle:自噬的分子标志物
- Author:
Qi ZHU
1
;
Fang LIN
1
Author Information
1. Soochow University School of Pharmaceutical Science, Suzhou 215123, China
- Publication Type:SPECIAL REPORTS
- Keywords:
autophagy;
macroautophagy;
chaperon-mediated autophagy;
mitophagy;
molecular marker
- From:
Acta Pharmaceutica Sinica
2016;51(1):33-
- CountryChina
- Language:Chinese
-
Abstract:
Autophagy is a physiological process which delivers the mutant cytoplasmic proteins and dysfunctional subcellular organs into lysosomes for degradation to generate fuel in the deficiency conditions. It is mainly classified into macroautophagy, microautophagy and chaperon-mediated autophagy (CMA), as well as the selective autophagy such as mitophagy and aggrephagy. This review mainly introduces the key molecular markers of macroautophagy, CMA and mitophagy.