Histological assessment of reversal of liver fibrosis and cirrhosis
10.3969/j.issn.1001-5256.2019.04.002
- VernacularTitle:肝纤维化和肝硬化逆转的组织学评价
- Author:
Yongjian ZHENG
1
;
Yan WANG
Author Information
1. State Key Laboratory of Organ Failure Research, Guangdong Provincial Research Center for Liver Fibrosis, Institute of Hepatology, Southern Medical University, Central Laboratory of Southern Medical University, Southern Medical University, Guangzhou 510515, China
- Publication Type:Research Article
- Keywords:
liver cirrhosis;
hepatitis, chronic;
fatty liver;
histology
- From:
Journal of Clinical Hepatology
2019;35(4):709-713
- CountryChina
- Language:Chinese
-
Abstract:
Liver fibrogenesis is a common pathway of pathological progression of chronic liver injuries. The diagnosis of liver fibrosis provides an important basis for treatment decision-making and prognostic evaluation of chronic liver diseases. With the rapid development of therapeutics, many new clinical issues have emerged, which requires new techniques for the diagnosis of liver fibrosis. At present, histological assessment remains the most reliable method for a definite diagnosis of liver fibrosis and cirrhosis. With reference to related clinical articles and data, this article analyzes the clinical value and research directions of histological assessment in chronic liver disease management and diagnosis of liver fibrosis/cirrhosis and its reversal.