Research progress of microbial biomarkers of early childhood caries
- Author:
HAN Xuan
1
;
HUO Yuanyuan
2
,
3
;
ZHANG Qiong
1
;
LI Yuqing
2
;
ZOU Jing
1
Author Information
- Publication Type:Review
- Keywords: Early childhood caries; Microorganism; Biomarker; Preschool children; Dental caries
- From: Journal of Prevention and Treatment for Stomatological Diseases 2018;26(6):391-395
- CountryChina
- Language:Chinese
- Abstract: The microorganisms in a healthy child’s oral environment survive in certain proportions and form a stable dynamic balance with the host. If this balance is disrupted, some of the microorganisms become cariogenic microbes and cause early childhood caries (ECC). The changes of cariogenic microbes in this process could be used as biomarkers to assess the caries risk of children and forecast the development of ECC. The relative indices of Streptococcus mutans and the closely related Candida albicans, Bifidobacterium and Streptococci sanguinis may be used as biomarkers to diagnose the susceptibility of children to caries. The detection rate and detection level of Lactobacillus may provide a reference for judging the rate of ECC development.
- Full text:低龄儿童龋致龋微生物相关生物标志物的研究进展.pdf
