Pathological Relationship between Intestinal Flora and Osteoarthritis and Intervention Mechanism of Chinese Medicine.
10.1007/s11655-019-3224-2
- Author:
Yong-Rong WU
1
;
Gao-Yan KUANG
2
;
Fang-Guo LU
3
;
Heng-Xin WANG
4
;
Min LU
2
;
Qing ZHOU
5
Author Information
1. TAN Xin-hua Famous Medical Studio, The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, 410007, China.
2. Department of Orthopedics, The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, 410007, China.
3. Department of Medical College, Hunan University of Chinese Medicine, Changsha, 410208, China.
4. Hinye Pharmaceutical Co., Ltd., Changsha, 410331, China.
5. TAN Xin-hua Famous Medical Studio, The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, 410007, China. 310094@hnucm.edu.cn.
- Publication Type:Journal Article
- Keywords:
intestinal flora;
mechanism of Chinese medicine;
osteoarthritis;
pathogenesis;
treatment
- From:
Chinese journal of integrative medicine
2019;25(9):716-720
- CountryChina
- Language:English
-
Abstract:
Chinese medicine (CM) has a good clinical effect on osteoarthritis (OA), but the mechanism is not very clear. Evidence-based medicine researches have shown that intestinal flora plays a role in the pathogenesis and succession of OA. Intestinal flora affects the efficacy of CM, and CM can affect the balance of intestinal flora. This paper focuses on the relationship between intestinal flora, intestinal microenvironment, brain-gut axis, metabolic immunity and OA, and preliminarily expound the significance of intestinal flora in the pathogenesis of OA and the mechanism of CM intervention. The above discussion will be of great significance in the prevention and treatment of OA by CM from the perspective of intestinal flora.
