Metabonome in Early Diagnosis of Renal Cell Carcinoma.
10.3881/j.issn.1000-503X.10957
- Author:
Zhan WANG
1
;
Yu Shi ZHANG
1
Author Information
1. Department of Urology,PUMC Hospital,CAMS and PUMC,Beijing 100730,Chinas.
- Publication Type:Journal Article
- Keywords:
early diagnosis;
metabolome;
metabolomics;
renal cell carcinoma
- MeSH:
Biomarkers, Tumor;
Carcinoma, Renal Cell;
diagnosis;
Early Detection of Cancer;
Humans;
Kidney Neoplasms;
diagnosis;
Metabolome;
Prognosis
- From:
Acta Academiae Medicinae Sinicae
2019;41(5):709-713
- CountryChina
- Language:Chinese
-
Abstract:
Renal cell carcinoma(RCC)is one of the most common malignant tumors in the urinary system.Many patients have already been in the advanced stage at the first medical consultation and the prognosis is dismal.Metabonomics searches for differential metabolomes through high-throughput analysis of endogenous metabolites showing high potential in the early diagnosis of RCC and the investigations on its pathophysiological mechanisms.Metabonomics techniques are also useful for identifying tumor markers,which will help to enable early diagnosis and improve clinical prognosis of RCC.
