Recent achievements in the microbiological etiology of dental caries.

VernacularTitle:龋病微生物因素研究进展
Author: Chen JING ¹ ; Cheng LEI ¹ ; Zhou XUEDONG ¹ ; Peng XIAN ¹
Author Information

1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Publication Type:Journal Article
Keywords: Streptococcus mutans; core microbiota; dental caries; etiology; oral microbiota
MeSH: Dental Caries; metabolism; Humans; Microbiota; Mouth; metabolism; Streptococcus mutans; pathogenicity
From: West China Journal of Stomatology 2018;36(1):104-108
CountryChina
Language:Chinese
Abstract: Dental caries is the most common chronic infectious disease of the oral cavity. The bacterium Streptococcus mutans is the sole pathogen that causes this disease. However, substantial evidence suggests that prevention and treatment strategies developed from traditional "cariogenic pathogen theory" are inefficient in reducing the prevalence of dental caries. An increasing number of individuals adopt the ecological view of the microbiota in the pathogenesis of dental caries. Recent technological improvements have enabled the detection and analysis of oral microorganisms, and many studies have focused on this area. The core microbiota is defined as a cluster of microbes playing critical roles in the initial and development phases of dental caries and may provide future direction for microorganism-related etiological studies.