Study of characteristic ions in frequently-used traditional Chinese medicinal materials derived from animal bile and its application.
10.19540/j.cnki.cjcmm.20180105.014
- Author:
Yan SHI
1
;
Jing XIONG
1
;
Feng WEI
1
;
Shuang-Cheng MA
1
Author Information
1. National Institutes for Food and Drug Control, Beijing 100050, China.
- Publication Type:Journal Article
- Keywords:
LC-MS;
artificial cow-bezoar;
bear bile;
cattle bile;
cow-bezoar;
cultivated cow-bezoar in vitro;
pig bile;
sheep bile
- MeSH:
Animals;
Bezoars;
Bile;
chemistry;
Cattle;
Chromatography, High Pressure Liquid;
Ions;
chemistry;
Mass Spectrometry;
Medicine, Chinese Traditional;
Species Specificity;
Swine;
Ursidae
- From:
China Journal of Chinese Materia Medica
2018;43(4):651-658
- CountryChina
- Language:Chinese
-
Abstract:
A LC-MS method was established for study of characteristic ions in frequently-used traditional Chinese medicinal materials derived from animal bile. UPLC-Q-TOF was used in the data acquisition work, then, the software of MarkerLynxTM v.4.1 was performed in the chemometric analysis of data. Besides, selected ion chromatograms of these bile acid ions were comparative studied. Better results were gained in the specificity identification of pig bile, bear bile, cultivated cow-bezoar , artificial cow-bezoar and some compound preparations(Hugan tablet and Rengongniuhuang Jiaxiaozuo capsule) by this method. The method is suitable for the specificity identification of pig bile, bear bile, cultivated cow-bezoar , artificial cow-bezoar and compound preparations containing these medicinal materials.
